<i>Mycobacterium tuberculosis</i> Promotes Apoptosis in Human Neutrophils by Activating Caspase-3 and Altering Expression of Bax/Bcl-xL Via an Oxygen-Dependent Pathway

Abstract In addition to direct bactericidal activities, such as phagocytosis and generation of reactive oxygen species (ROS), neutrophils can regulate the inflammatory response by undergoing apoptosis. We found that infection of human neutrophils with Mycobacterium tuberculosis (Mtb) induced rapid c...

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Bibliographic Details
Main Authors: Nasrin Perskvist, Min Long, Olle Stendahl, Limin Zheng
Format: Artigo
Language:English
Published: 2002
Online Access:https://doi.org/10.4049/jimmunol.168.12.6358
https://journals.aai.org/jimmunol/article-pdf/168/12/6358/1145867/6358.pdf
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