Homology-based inference sets the bar high for protein function prediction

Homology-based inference sets the bar high for protein function prediction

Any method that de novo predicts protein function should do better than random. More challenging, it also ought to outperform simple homology-based inference.Here, we describe a few methods that predict protein function exclusively through homology. Together, they set the bar or lower limit for futu...

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Hlavní autoři: Tobias Hamp, Rebecca Kaßner, Stefan Seemayer, Esmeralda Vicedo, Christian Schaefer, Dominik Achten, Florian Auer, Ariane C. Boehm, Tatjana Braun, Maximilian Hecht, B. Mark Heron, Peter Hönigschmid, Thomas A. Hopf, Stefanie Kaufmann, Michael Kiening, Denis Krompaß, Cedric Landerer, Yannick Mahlich, Manfred Roos, Burkhard Rost
Médium: Artigo
Jazyk:angličtina
Vydáno: 2013
On-line přístup:https://doi.org/10.1186/1471-2105-14-s3-s7
https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-14-S3-S7
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https://doi.org/10.1186/1471-2105-14-s3-s7
https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-14-S3-S7

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