The anti-aging gene KLOTHO is a novel target for epigenetic silencing in human cervical carcinoma

The anti-aging gene KLOTHO is a novel target for epigenetic silencing in human cervical carcinoma

Klotho was originally characterized as an anti-aging gene that predisposed Klotho-deficient mice to a premature aging-like syndrome. Recently, KLOTHO was reported to function as a secreted Wnt antagonist and as a tumor suppressor. Epigenetic gene silencing of secreted Wnt antagonists is considered a...

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Main Authors: Jaehyouk Lee, Dongjun Jeong, Jin‐Sun Kim, Soonduck Lee, Jin-Hwa Park, Boogi Chang, Samil Jung, Lisha Yi, Young‐Soo Han, Young Yang, Keun Tae Kim, Jong‐Seok Lim, Inchul Yang, Seob Jeon, Dong Ho Bae, Chang‐Jin Kim, Myeong‐Sok Lee
Format: Artigo
Language:English
Published: 2010
Online Access:https://doi.org/10.1186/1476-4598-9-109
https://molecular-cancer.biomedcentral.com/counter/pdf/10.1186/1476-4598-9-109
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https://doi.org/10.1186/1476-4598-9-109
https://molecular-cancer.biomedcentral.com/counter/pdf/10.1186/1476-4598-9-109

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