The anti-aging gene KLOTHO is a novel target for epigenetic silencing in human cervical carcinoma
Klotho was originally characterized as an anti-aging gene that predisposed Klotho-deficient mice to a premature aging-like syndrome. Recently, KLOTHO was reported to function as a secreted Wnt antagonist and as a tumor suppressor. Epigenetic gene silencing of secreted Wnt antagonists is considered a...
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Main Authors: | Jaehyouk Lee, Dongjun Jeong, Jin‐Sun Kim, Soonduck Lee, Jin-Hwa Park, Boogi Chang, Samil Jung, Lisha Yi, Young‐Soo Han, Young Yang, Keun Tae Kim, Jong‐Seok Lim, Inchul Yang, Seob Jeon, Dong Ho Bae, Chang‐Jin Kim, Myeong‐Sok Lee |
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Formato: | Artigo |
Idioma: | inglés |
Publicado: |
2010
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Acceso en liña: | https://doi.org/10.1186/1476-4598-9-109 https://molecular-cancer.biomedcentral.com/counter/pdf/10.1186/1476-4598-9-109 |
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