The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications

The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications

Glutamatergic signaling through N-methyl-D-aspartate receptors (NMDARs) is required for synaptic plasticity. Disruptions in glutamatergic signaling are proposed to contribute to the behavioral and cognitive deficits observed in schizophrenia (SZ). One possible source of compromised glutamatergic fun...

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Main Authors: Nikisha Carty, Jin Xu, PU Kurup, Jonathan Brouillette, Susan Goebel-Goody, Daniel Austin, P Yuan, G Chen, Paulo Rogério Corrêa, V. Haroutunian, Christopher Pittenger, Paul J. Lombroso
Format: Artigo
Language:English
Published: 2012
Online Access:https://doi.org/10.1038/tp.2012.63
https://www.nature.com/articles/tp201263.pdf
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https://doi.org/10.1038/tp.2012.63
https://www.nature.com/articles/tp201263.pdf

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