CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris

Engagement of the B7 family of molecules on antigen-presenting cells with their T cell–associated ligands, CD28 and CD152 (cytotoxic T lymphocyte–associated antigen-4 [CTLA-4]), provides a pivotal costimulatory signal in T-cell activation. We investigated the role of the CD28/CD152 pathway in psoria...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Judith R. Abrams, Mark Lebwohl, Cynthia Guzzo, Brian V. Jegasothy, Michael Goldfarb, Bernard S. Goffe, Alan Menter, Nicholas J. Lowe, Gerald G. Krueger, Michael J. Brown, Russell Weiner, Martin Birkhofer, Garvin L. Warner, Karen Berry, Peter S. Linsley, James G. Krueger, Hans D. Ochs, Susan L. Kelley, Sewon Kang
Materialtyp: Artigo
Språk:engelska
Publicerad: 1999
Länkar:https://doi.org/10.1172/jci5857
http://www.jci.org/articles/view/5857/files/pdf
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!