CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris
Engagement of the B7 family of molecules on antigen-presenting cells with their T cell–associated ligands, CD28 and CD152 (cytotoxic T lymphocyte–associated antigen-4 [CTLA-4]), provides a pivotal costimulatory signal in T-cell activation. We investigated the role of the CD28/CD152 pathway in psoria...
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | inglés |
| Publicado: |
1999
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| Acceso en liña: | https://doi.org/10.1172/jci5857 http://www.jci.org/articles/view/5857/files/pdf |
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