Cleavage Specificity of the UL48 Deubiquitinating Protease Activity of Human Cytomegalovirus and the Growth of an Active-Site Mutant Virus in Cultured Cells

The human cytomegalovirus (HCMV) open reading frame UL48 encodes a 253-kDa tegument protein that is closely associated with the capsid and was recently shown to have ubiquitin-specific protease activity (J. Wang, A. N. Loveland, L. M. Kattenhorn, H. L. Ploegh, and W. Gibson, J. Virol. 80:6003-6012,...

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Bibliographic Details
Main Authors: Eui Tae Kim, Se Eun Oh, Yun-Ok Lee, Wade Gibson, Jin-Hyun Ahn
Format: Artigo
Language:English
Published: 2009
Online Access:https://doi.org/10.1128/jvi.00411-09
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