Ligand-Activated PPARα-Dependent DNA Demethylation Regulates the Fatty Acid β-Oxidation Genes in the Postnatal Liver

The metabolic function of the liver changes sequentially during early life in mammals to adapt to the marked changes in nutritional environment. Accordingly, hepatic fatty acid β-oxidation is activated after birth to produce energy from breast milk lipids. However, how it is induced during the neona...

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Príomhchruthaitheoirí: Tatsuya Ehara, Yasutomi Kamei, Xunmei Yuan, Mayumí Takáhashi, Sayaka Kanai, Erina Tamura, Kazutaka Tsujimoto, Takashi Tamiya, Yoshimi Nakagawa, Hitoshi Shimano, Takako Takai‐Igarashi, Izuho Hatada, Takayoshi Suganami, Koshi Hashimoto, Yoshihiro Ogawa
Formáid: Artigo
Teanga:Béarla
Foilsithe / Cruthaithe: 2014
Rochtain ar líne:https://doi.org/10.2337/db14-0158
https://diabetes.diabetesjournals.org/content/diabetes/64/3/775.full.pdf
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