The Transcriptional Specificity of NF-κB Dimers Is Coded within the κB DNA Response Elements

Nuclear factor κB (NF-κB) regulates gene expression by binding to specific DNA elements, known collectively as κB sites, that are contained within the promoters/enhancers of target genes. We found that the identity of the central base pair (bp) of κB sites profoundly affects the transcriptional acti...

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Hlavní autoři: Vivien Ya‐Fan Wang, Wendy Huang, Masataka Asagiri, Nathanael J. Spann, Alexander Hoffmann, Christopher K. Glass, Gourisankar Ghosh
Médium: Artigo
Jazyk:angličtina
Vydáno: 2012
On-line přístup:https://doi.org/10.1016/j.celrep.2012.08.042
https://www.cell.com/article/S2211124712003154/pdf
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