Preventing β-Cell Loss and Diabetes With Calcium Channel Blockers
Although loss of functional β-cell mass is a hallmark of diabetes, no treatment approaches that halt this process are currently available. We recently identified thioredoxin-interacting protein (TXNIP) as an attractive target in this regard. Glucose and diabetes upregulate β-cell TXNIP expression, a...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2012
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| Online Access: | https://doi.org/10.2337/db11-0955 https://diabetes.diabetesjournals.org/content/diabetes/61/4/848.full.pdf |
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