Physical Association with Ras Enhances Activation of Membrane-bound Raf (RafCAAX)
The transforming activity of artificially membrane-targeted Raf1 suggests that Ras-mediated recruitment of Raf1 to the plasma membrane is an important step in Raf1 activation. Cellular Ras is concentrated in the caveolae, a microdomain of the plasma membrane that is highly enriched in caveolin, glyc...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
1997
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| 在线阅读: | https://doi.org/10.1074/jbc.272.16.10345 http://www.jbc.org/article/S0021925818406941/pdf |
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