Physical Association with Ras Enhances Activation of Membrane-bound Raf (RafCAAX)
The transforming activity of artificially membrane-targeted Raf1 suggests that Ras-mediated recruitment of Raf1 to the plasma membrane is an important step in Raf1 activation. Cellular Ras is concentrated in the caveolae, a microdomain of the plasma membrane that is highly enriched in caveolin, glyc...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Language: | English |
| Published: |
1997
|
| Online Access: | https://doi.org/10.1074/jbc.272.16.10345 http://www.jbc.org/article/S0021925818406941/pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|