Virus-Dependent Phosphorylation of the IRF-3 Transcription Factor Regulates Nuclear Translocation, Transactivation Potential, and Proteasome-Mediated Degradation

ABSTRACTThe interferon regulatory factors (IRF) consist of a growing family of related transcription proteins first identified as regulators of the alpha beta interferon (IFN-α/β) gene promoters, as well as the interferon-stimulated response element (ISRE) of some IFN-stimulated genes. IRF-3 was ori...

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Hlavní autoři: Rongtuan Lin, Christophe Heylbroeck, Paula M. Pitha, John Hiscott
Médium: Artigo
Jazyk:angličtina
Vydáno: 1998
On-line přístup:https://doi.org/10.1128/mcb.18.5.2986
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