Leukemogenesis Caused by Incapacitated GATA-1 Function
GATA-1 is essential for the development of erythroid and megakaryocytic lineages. We found that GATA-1 gene knockdown female (GATA-1.05/X) mice frequently develop a hematopoietic disorder resembling myelodysplastic syndrome that is characterized by the accumulation of progenitors expressing low leve...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | anglais |
| Publié: |
2004
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| Accès en ligne: | https://doi.org/10.1128/mcb.24.24.10814-10825.2004 |
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