Endotoxin-Induced Maturation of MyD88-Deficient Dendritic Cells

Abstract LPS, a major component of the cell wall of Gram-negative bacteria, can induce a variety of biological responses including cytokine production from macrophages, B cell proliferation, and endotoxin shock. All of them were completely abolished in MyD88-deficient mice, indicating the essential...

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Bibliographic Details
Main Authors: Tsuneyasu Kaisho, Osamu Takeuchi, Taro Kawai, Katsuaki Hoshino, Shizuo Akira
Format: Artigo
Language:English
Published: 2001
Online Access:https://doi.org/10.4049/jimmunol.166.9.5688
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