Recombinant anti‐podoplanin (NZ‐1) immunotoxin for the treatment of malignant brain tumors

Our study demonstrates the glioma tumor antigen podoplanin to be present at very high levels (>90%) in both glioblastoma (D2159MG, D08-0308MG and D08-0493MG) and medulloblastoma (D283MED, D425MED and DAOY) xenografts and cell line. We constructed a novel recombinant single-chain antibody variable...

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Bibliographic Details
Main Authors: Vidyalakshmi Chandramohan, Xuhui Bao, Mika K. Kaneko, Yukinari Kato, Stephen T. Keir, Scott E. Szafranski, Chien‐Tsun Kuan, Ira Pastan, Darell D. Bigner
Format: Artigo
Language:English
Published: 2012
Online Access:https://doi.org/10.1002/ijc.27919
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.27919
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