Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer’s disease
Alzheimer's disease (AD) is a severe age-related neurodegenerative disorder characterized by accumulation of amyloid-β plaques and neurofibrillary tangles, synaptic and neuronal loss, and cognitive decline. Several genes have been implicated in AD, but chromatin state alterations during neurode...
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Main Authors: | , , , , , , |
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格式: | Artigo |
语言: | 英语 |
出版: |
2015
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在线阅读: | https://doi.org/10.1038/nature14252 https://www.nature.com/articles/nature14252.pdf |
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