Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo

Cellular responses to both physiological and pathological DNA double-strand breaks are initiated through activation of the evolutionarily conserved ataxia telangiectasia mutated (ATM) kinase. Upon DNA damage, an activation mechanism involving autophosphorylation has been reported to allow ATM to pho...

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Bibliografske podrobnosti
Main Authors: J. Daniel, Manuela Pellegrini, Ji‐Hoon Lee, Tanya T. Paull, Lionel Feigenbaum, André Nussenzweig
Format: Artigo
Jezik:angleščina
Izdano: 2008
Online dostop:https://doi.org/10.1083/jcb.200805154
https://rupress.org/jcb/article-pdf/183/5/777/1339781/jcb_200805154.pdf
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