Noninvasive Detection of Response and Resistance in <i>EGFR</i>-Mutant Lung Cancer Using Quantitative Next-Generation Genotyping of Cell-Free Plasma DNA

Abstract Purpose: Tumor genotyping using cell-free plasma DNA (cfDNA) has the potential to allow noninvasive assessment of tumor biology, yet many existing assays are cumbersome and vulnerable to false-positive results. We sought to determine whether droplet digital PCR (ddPCR) of cfDNA would allow...

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Main Authors: Geoffrey R. Oxnard, Cloud P. Paweletz, Yanan Kuang, Stacy L. Mach, Allison O’Connell, Melissa M. Messineo, Jason J. Luke, Mohit Butaney, Paul T. Kirschmeier, David M. Jackman, Pasi A. Jänne
格式: Artigo
语言:英语
出版: 2014
在线阅读:https://doi.org/10.1158/1078-0432.ccr-13-2482
https://clincancerres.aacrjournals.org/content/clincanres/20/6/1698.full.pdf
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