Targeting Akt and Heat Shock Protein 90 Produces Synergistic Multiple Myeloma Cell Cytotoxicity in the Bone Marrow Microenvironment
Abstract Purpose: We hypothesized that targeting both Akt and heat shock protein (HSP) 90 would induce cytotoxic activity against multiple myeloma (MM) cells and target the bone marrow (BM) microenvironment to inhibit angiogenesis, osteoclast formation, as well as migration and adhesion of MM cells....
-д хадгалсан:
| Үндсэн зохиолчид: | , , , , , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Хэл сонгох: | англи |
| Хэвлэсэн: |
2008
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| Онлайн хандалт: | https://doi.org/10.1158/1078-0432.ccr-07-1299 https://aacrjournals.org/clincancerres/article-pdf/14/3/865/1979022/865.pdf |
| Шошгууд: |
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