miR-182 and miR-10a Are Key Regulators of Treg Specialisation and Stability during Schistosome and Leishmania-associated Inflammation

miR-182 and miR-10a Are Key Regulators of Treg Specialisation and Stability during Schistosome and Leishmania-associated Inflammation

A diverse suite of effector immune responses provide protection against various pathogens. However, the array of effector responses must be immunologically regulated to limit pathogen- and immune-associated damage. CD4+Foxp3+ regulatory T cells (Treg) calibrate immune responses; however, how Treg ce...

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Main Authors: Samir N. P. Kelada, Praveen Sethupathy, Isobel Okoye, Eleni Kistasis, Stephanie Czieso, Sandra White, David B. Chou, Craig Martens, Stacy Ricklefs, Kimmo Virtaneva, Dan E. Sturdevant, Stephen F. Porcella, Yasmine Belkaid, Thomas A. Wynn, Mark S. Wilson
Format: Artigo
Language:English
Published: 2013
Online Access:https://doi.org/10.1371/journal.ppat.1003451
https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003451&type=printable
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https://doi.org/10.1371/journal.ppat.1003451
https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003451&type=printable

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