Composition-based statistics and translated nucleotide searches: Improving the TBLASTN module of BLAST

TBLASTN is a mode of operation for BLAST that aligns protein sequences to a nucleotide database translated in all six frames. We present the first description of the modern implementation of TBLASTN, focusing on new techniques that were used to implement composition-based statistics for translated n...

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Main Authors: E. Michael Gertz, Yi‐Kuo Yu, Richa Agarwala, Alejandro A. Schäffer, Stephen F. Altschul
Formato: Artigo
Idioma:inglés
Publicado: 2006
Acceso en liña:https://doi.org/10.1186/1741-7007-4-41
https://bmcbiol.biomedcentral.com/counter/pdf/10.1186/1741-7007-4-41
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