An N-Terminal Molecular Form of Parathyroid Hormone (PTH) Distinct from hPTH(1–84) Is Overproduced in Parathyroid Carcinoma

Abstract Background: A new parathyroid hormone (PTH) species, the N-terminal PTH form (N-PTH), is distinct from intact human PTH of 84 amino acid residues [hPTH(1–84)] and is recognized in a 3rd-generation assay of “whole” PTH (wPTH; the 1–2 epitope) but not in a 2nd-generation assay of “total” PTH...

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Main Authors: Mishaela R. Rubin, Shonni J. Silverberg, P D'Amour, Jean‐Hugues Brossard, Louise Rousseau, James Sliney, Tom Cantor, John P. Bilezikian
格式: Artigo
语言:英语
出版: 2007
在线阅读:https://doi.org/10.1373/clinchem.2007.085506
https://academic.oup.com/clinchem/article-pdf/53/8/1470/32687952/clinchem1470.pdf
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