Hepatitis C Virus Core Protein Blocks Interferon Signaling by Interaction with the STAT1 SH2 Domain
ABSTRACT Emerging data have indicated that hepatitis C virus (HCV) subverts the host antiviral response to ensure its persistence. We previously demonstrated that HCV protein expression suppresses type I interferon (IFN) signaling by leading to the reduction of phosphorylated STAT1 (P-STAT1). We als...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | anglais |
| Publié: |
2006
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| Accès en ligne: | https://doi.org/10.1128/jvi.00459-06 |
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