Telomerase expression and telomere length in breast cancer and their associations with adjuvant treatment and disease outcome

Telomere length plays important roles in maintaining genome stability and regulating cell replication and death. Telomerase has functions not only to extend telomere length but also to repair DNA damage. Studies have shown that telomerase may increase cancer cell resistance to DNA-damaging anticance...

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Bibliographic Details
Main Authors: Lingeng Lu, Chong Zhang, Gongjian Zhu, Melinda L. Irwin, Harvey A. Risch, Guido Menato, Marco Mitidieri, Dionyssios Katsaros, Herbert Yu
Format: Artigo
Language:English
Published: 2011
Online Access:https://doi.org/10.1186/bcr2893
https://breast-cancer-research.biomedcentral.com/counter/pdf/10.1186/bcr2893
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