Telomerase expression and telomere length in breast cancer and their associations with adjuvant treatment and disease outcome

Telomere length plays important roles in maintaining genome stability and regulating cell replication and death. Telomerase has functions not only to extend telomere length but also to repair DNA damage. Studies have shown that telomerase may increase cancer cell resistance to DNA-damaging anticance...

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Hlavní autoři: Lingeng Lu, Chong Zhang, Gongjian Zhu, Melinda L. Irwin, Harvey A. Risch, Guido Menato, Marco Mitidieri, Dionyssios Katsaros, Herbert Yu
Médium: Artigo
Jazyk:angličtina
Vydáno: 2011
On-line přístup:https://doi.org/10.1186/bcr2893
https://breast-cancer-research.biomedcentral.com/counter/pdf/10.1186/bcr2893
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