Telomerase expression and telomere length in breast cancer and their associations with adjuvant treatment and disease outcome
Telomere length plays important roles in maintaining genome stability and regulating cell replication and death. Telomerase has functions not only to extend telomere length but also to repair DNA damage. Studies have shown that telomerase may increase cancer cell resistance to DNA-damaging anticance...
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Hlavní autoři: | Lingeng Lu, Chong Zhang, Gongjian Zhu, Melinda L. Irwin, Harvey A. Risch, Guido Menato, Marco Mitidieri, Dionyssios Katsaros, Herbert Yu |
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Médium: | Artigo |
Jazyk: | angličtina |
Vydáno: |
2011
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On-line přístup: | https://doi.org/10.1186/bcr2893 https://breast-cancer-research.biomedcentral.com/counter/pdf/10.1186/bcr2893 |
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