GCP6 is a substrate of Plk4 and required for centriole duplication
Centriole duplication occurs once per cell cycle and requires Plk4, a member of the Polo-like kinase family. A key component of the centrosome is the γ-tubulin ring complex (γ-TuRC) that nucleates microtubules. GCP6 is a member of the γ-TuRC, but its role in human cells and the regulation of its fun...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2012
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| 在线阅读: | https://doi.org/10.1242/jcs.093930 https://jcs.biologists.org/content/joces/125/2/486.full.pdf |
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