A Phase I-II Study of Docetaxel and Atrasentan in Men with Castration-Resistant Metastatic Prostate Cancer

Abstract Purpose: The primary aims of this phase I-II study were to determine the maximum tolerated dose, dose-limiting toxicity, pharmacokinetics, and preliminary efficacy of the combination of docetaxel and the endothelin A receptor antagonist atrasentan as first-line treatment for men with metast...

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Main Authors: Andrew J. Armstrong, Patricia Creel, James Turnbull, Cassandra N. Moore, Tracy A. Jaffe, Sherri Haley, William P. Petros, Sarah Yenser, Jon P. Gockerman, Darryl J. Sleep, Herbert I. Hurwitz, Daniel J. George
格式: Artigo
语言:英语
出版: 2008
在线阅读:https://doi.org/10.1158/1078-0432.ccr-08-1085
https://aacrjournals.org/clincancerres/article-pdf/14/19/6270/1978025/6270.pdf
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