A Phase I-II Study of Docetaxel and Atrasentan in Men with Castration-Resistant Metastatic Prostate Cancer

Abstract Purpose: The primary aims of this phase I-II study were to determine the maximum tolerated dose, dose-limiting toxicity, pharmacokinetics, and preliminary efficacy of the combination of docetaxel and the endothelin A receptor antagonist atrasentan as first-line treatment for men with metast...

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Hlavní autoři: Andrew J. Armstrong, Patricia Creel, James Turnbull, Cassandra N. Moore, Tracy A. Jaffe, Sherri Haley, William P. Petros, Sarah Yenser, Jon P. Gockerman, Darryl J. Sleep, Herbert I. Hurwitz, Daniel J. George
Médium: Artigo
Jazyk:angličtina
Vydáno: 2008
On-line přístup:https://doi.org/10.1158/1078-0432.ccr-08-1085
https://aacrjournals.org/clincancerres/article-pdf/14/19/6270/1978025/6270.pdf
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