Telomere Length Dynamics and Chromosomal Instability in Cells Derived from Telomerase Null Mice

To study the effect of continued telomere shortening on chromosome stability, we have analyzed the telomere length of two individual chromosomes (chromosomes 2 and 11) in fibroblasts derived from wild-type mice and from mice lacking the mouse telomerase RNA (mTER) gene using quantitative fluorescenc...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: M. Prakash Hande, Enrique Samper, Peter M. Lansdorp, Marı́a A. Blasco
Hōputu: Artigo
Reo:Ingarihi
I whakaputaina: 1999
Urunga tuihono:https://doi.org/10.1083/jcb.144.4.589
http://jcb.rupress.org/content/144/4/589.full.pdf
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