Telomere Length Dynamics and Chromosomal Instability in Cells Derived from Telomerase Null Mice

To study the effect of continued telomere shortening on chromosome stability, we have analyzed the telomere length of two individual chromosomes (chromosomes 2 and 11) in fibroblasts derived from wild-type mice and from mice lacking the mouse telomerase RNA (mTER) gene using quantitative fluorescenc...

詳細記述

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書誌詳細
主要な著者: M. Prakash Hande, Enrique Samper, Peter M. Lansdorp, Marı́a A. Blasco
フォーマット: Artigo
言語:英語
出版事項: 1999
オンライン・アクセス:https://doi.org/10.1083/jcb.144.4.589
http://jcb.rupress.org/content/144/4/589.full.pdf
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