Telomere Length Dynamics and Chromosomal Instability in Cells Derived from Telomerase Null Mice

To study the effect of continued telomere shortening on chromosome stability, we have analyzed the telomere length of two individual chromosomes (chromosomes 2 and 11) in fibroblasts derived from wild-type mice and from mice lacking the mouse telomerase RNA (mTER) gene using quantitative fluorescenc...

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Autori principali: M. Prakash Hande, Enrique Samper, Peter M. Lansdorp, Marı́a A. Blasco
Natura: Artigo
Lingua:inglese
Pubblicazione: 1999
Accesso online:https://doi.org/10.1083/jcb.144.4.589
http://jcb.rupress.org/content/144/4/589.full.pdf
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