Telomere Length Dynamics and Chromosomal Instability in Cells Derived from Telomerase Null Mice

To study the effect of continued telomere shortening on chromosome stability, we have analyzed the telomere length of two individual chromosomes (chromosomes 2 and 11) in fibroblasts derived from wild-type mice and from mice lacking the mouse telomerase RNA (mTER) gene using quantitative fluorescenc...

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Príomhchruthaitheoirí: M. Prakash Hande, Enrique Samper, Peter M. Lansdorp, Marı́a A. Blasco
Formáid: Artigo
Teanga:Béarla
Foilsithe / Cruthaithe: 1999
Rochtain ar líne:https://doi.org/10.1083/jcb.144.4.589
http://jcb.rupress.org/content/144/4/589.full.pdf
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