Telomere Length Dynamics and Chromosomal Instability in Cells Derived from Telomerase Null Mice
To study the effect of continued telomere shortening on chromosome stability, we have analyzed the telomere length of two individual chromosomes (chromosomes 2 and 11) in fibroblasts derived from wild-type mice and from mice lacking the mouse telomerase RNA (mTER) gene using quantitative fluorescenc...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
1999
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| Online Access: | https://doi.org/10.1083/jcb.144.4.589 http://jcb.rupress.org/content/144/4/589.full.pdf |
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