Telomere Length Dynamics and Chromosomal Instability in Cells Derived from Telomerase Null Mice

To study the effect of continued telomere shortening on chromosome stability, we have analyzed the telomere length of two individual chromosomes (chromosomes 2 and 11) in fibroblasts derived from wild-type mice and from mice lacking the mouse telomerase RNA (mTER) gene using quantitative fluorescenc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: M. Prakash Hande, Enrique Samper, Peter M. Lansdorp, Marı́a A. Blasco
Fformat: Artigo
Iaith:Saesneg
Cyhoeddwyd: 1999
Mynediad Ar-lein:https://doi.org/10.1083/jcb.144.4.589
http://jcb.rupress.org/content/144/4/589.full.pdf
Tagiau: Ychwanegu Tag
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