Deletion of CCK<sub>2</sub>Receptor in Mice Results in an Upregulation of the Endogenous Opioid System
Stimulation of the brain CCK<sub>2</sub> receptor by the C-terminal octapeptide CCK<sub>8</sub> of cholecystokinin (CCK) negatively modulates opioid responses. This suggests the existence of physiologically relevant interactions between endogenous CCK and opioid peptides, ope...
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Main Authors: | , , , , , , , |
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Format: | Artigo |
Language: | English |
Published: |
2002
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Online Access: | https://doi.org/10.1523/jneurosci.22-05-02005.2002 https://www.jneurosci.org/content/jneuro/22/5/2005.full.pdf |
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