Genetic Progression and the Waiting Time to Cancer

Cancer results from genetic alterations that disturb the normal cooperative behavior of cells. Recent high-throughput genomic studies of cancer cells have shown that the mutational landscape of cancer is complex and that individual cancers may evolve through mutations in as many as 20 different canc...

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Main Authors: Niko Beerenwinkel, Tibor Antal, David Dingli, Arne Traulsen, Kenneth W. Kinzler, Victor E. Velculescu, Bert Vogelstein, Martin A. Nowak
格式: Artigo
语言:英语
出版: 2007
在线阅读:https://doi.org/10.1371/journal.pcbi.0030225
https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.0030225&type=printable
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