From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus
Insulin resistance in muscle and liver and β-cell failure represent the core pathophysiologic defects in type 2 diabetes. It now is recognized that the β-cell failure occurs much earlier and is more severe than previously thought. Subjects in the upper tertile of impaired glucose tolerance (IGT) are...
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| 主要作者: | |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2009
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| 在线阅读: | https://doi.org/10.2337/db09-9028 https://diabetesjournals.org/diabetes/article-pdf/58/4/773/303468/zdb00409000773.pdf |
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