From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus

Insulin resistance in muscle and liver and β-cell failure represent the core pathophysiologic defects in type 2 diabetes. It now is recognized that the β-cell failure occurs much earlier and is more severe than previously thought. Subjects in the upper tertile of impaired glucose tolerance (IGT) are...

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Hlavní autor: Ralph A. DeFronzo
Médium: Artigo
Jazyk:angličtina
Vydáno: 2009
On-line přístup:https://doi.org/10.2337/db09-9028
https://diabetesjournals.org/diabetes/article-pdf/58/4/773/303468/zdb00409000773.pdf
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