Engineering Mouse Chromosomes with Cre-<i>loxP</i>: Range, Efficiency, and Somatic Applications
Chromosomal rearrangements are important resources for genetic studies. Recently, a Cre-loxP-based method to introduce defined chromosomal rearrangements (deletions, duplications, and inversions) into the mouse genome (chromosome engineering) has been established. To explore the limits of this techn...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | 英语 |
| 出版: |
2000
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| 在線閱讀: | https://doi.org/10.1128/mcb.20.2.648-655.2000 |
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