Minichromosome maintenance helicase paralog MCM9 is dispensible for DNA replication but functions in germ-line stem cells and tumor suppression
Effective DNA replication is critical to the health and reproductive success of organisms. The six MCM2–7 proteins, which form the replicative helicase, are essential for high-fidelity replication of the genome. Many eukaryotes have a divergent paralog, MCM9, that was reported to be essential for lo...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Englisch |
| Veröffentlicht: |
2011
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| Online-Zugang: | https://doi.org/10.1073/pnas.1113524108 |
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