Mesothelin-specific CD8+ T Cell Responses Provide Evidence of In Vivo Cross-Priming by Antigen-Presenting Cells in Vaccinated Pancreatic Cancer Patients

Tumor-specific CD8+ T cells can potentially be activated by two distinct mechanisms of major histocompatibility complex class I–restricted antigen presentation as follows: direct presentation by tumor cells themselves or indirect presentation by professional antigen-presenting cells (APCs). However,...

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Hlavní autoři: Amy Thomas, Lynn M. Santarsiero, Eric R. Lutz, Todd D. Armstrong, Yi-Cheng Chen, Lan-Qing Huang, Daniel A. Laheru, Michael Goggins, Ralph H. Hruban, Elizabeth M. Jaffee
Médium: Artigo
Jazyk:angličtina
Vydáno: 2004
On-line přístup:https://doi.org/10.1084/jem.20031435
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