Nongenomic Androgen Activation of Phosphatidylinositol 3-Kinase/Akt Signaling Pathway in MC3T3-E1 Osteoblasts

Androgens have important effects on the bone metabolism. However, the effect and mechanism of androgen action on the osteoblasts remains unknown. Here we showed that androgens increase phosphorylation and nuclear translocation of Akt. siRNA-AR prevented androgen-induced Akt activation in MC3T3-E1 ce...

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Main Authors: Hong‐Yo Kang, Chung-Lung Cho, Kai-Lieh Huang, Jyh-Chwan Wang, Yueh‐Chiang Hu, Hui‐Kuan Lin, Chawnshang Chang, Ko-En Huang
格式: Artigo
语言:英语
出版: 2004
在线阅读:https://doi.org/10.1359/jbmr.040306
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1359/JBMR.040306
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