Nongenomic Androgen Activation of Phosphatidylinositol 3-Kinase/Akt Signaling Pathway in MC3T3-E1 Osteoblasts
Androgens have important effects on the bone metabolism. However, the effect and mechanism of androgen action on the osteoblasts remains unknown. Here we showed that androgens increase phosphorylation and nuclear translocation of Akt. siRNA-AR prevented androgen-induced Akt activation in MC3T3-E1 ce...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | engleski |
| Izdano: |
2004
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| Online pristup: | https://doi.org/10.1359/jbmr.040306 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1359/JBMR.040306 |
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