Slit2 Prevents Neutrophil Recruitment and Renal Ischemia-Reperfusion Injury

Slit2 Prevents Neutrophil Recruitment and Renal Ischemia-Reperfusion Injury

Neutrophils recruited to the postischemic kidney contribute to the pathogenesis of ischemia-reperfusion injury (IRI), which is the most common cause of renal failure among hospitalized patients. The Slit family of secreted proteins inhibits chemotaxis of leukocytes by preventing activation of Rho-fa...

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Main Authors: Swasti Chaturvedi, Darren A. Yuen, Amandeep Bajwa, Yiwei Huang, Christiane Sokollik, Liping Huang, Grace Y. Lam, Soumitra Tole, Guang-Ying Liu, J Pan, Lauren Chan, Yaro Sokolskyy, Manoj Puthia, Gabriela Godaly, Rohan John, Changsen Wang, Warren L. Lee, John H. Brumell, Mark D. Okusa, Lisa A. Robinson
Format: Artigo
Language:English
Published: 2013
Online Access:https://doi.org/10.1681/asn.2012090890
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https://doi.org/10.1681/asn.2012090890

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