Diabetes Causes Bone Marrow Endothelial Barrier Dysfunction by Activation of the RhoA–Rho-Associated Kinase Signaling Pathway

Diabetes Causes Bone Marrow Endothelial Barrier Dysfunction by Activation of the RhoA–Rho-Associated Kinase Signaling Pathway

Diabetes mellitus causes bone marrow (BM) microangiopathy. This study aimed to investigate the mechanisms responsible for BM endothelial dysfunction in diabetes mellitus.The analysis of differentially expressed transcripts in BM endothelial cells (BMECs) from type-1 diabetic and nondiabetic mice sho...

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Main Authors: Giuseppe Mangialardi, Rajesh Katare, Atsuhiko Oikawa, Marco Meloni, Carlotta Reni, Costanza Emanueli, Paolo Madeddu
Format: Artigo
Language:English
Published: 2013
Online Access:https://doi.org/10.1161/atvbaha.112.300424
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https://doi.org/10.1161/atvbaha.112.300424

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