Promoter Variation in the DC-SIGN–Encoding Gene CD209 Is Associated with Tuberculosis

Background Tuberculosis, which is caused by Mycobacterium tuberculosis, remains one of the leading causes of mortality worldwide. The C-type lectin DC-SIGN is known to be the major M. tuberculosis receptor on human dendritic cells. We reasoned that if DC-SIGN interacts with M. tuberculosis, as well...

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Hlavní autoři: Luis B. Barreiro, Olivier Neyrolles, Chantal Babb de Villiers, Ludovic Tailleux, Hélène Quach, Ken McElreavey, Paul D. van Helden, Eileen G. Hoal, Brigitte Gicquel, Lluı́s Quintana-Murci
Médium: Artigo
Jazyk:angličtina
Vydáno: 2005
On-line přístup:https://doi.org/10.1371/journal.pmed.0030020
https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.0030020&type=printable
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