PrPC Directly Interacts with Proteins Involved in Signaling Pathways

The cellular prion protein (PrP(C)) is a conserved glycoprotein predominantly expressed in neuronal cells. Its purpose in living cells is still enigmatic. To elucidate on its cellular function, we performed a yeast two-hybrid screen for interactors. We used murine PrP(C) (amino acids 23-231) as bait...

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Main Authors: Christian Spielhaupter, Hermann Schätzl
Formato: Artigo
Idioma:inglés
Publicado: 2001
Acceso en liña:https://doi.org/10.1074/jbc.m103289200
http://www.jbc.org/article/S0021925819826546/pdf
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